Vertex cystic fibrosis combination succeeds in late-stage trials

Vertex Pharmaceuticals said on Tuesday its Kalydeco cystic fibrosis treatment givenwith an experimental drug demonstrated significant improvements in lung function in a pair of late-stage trials the company plans to use to seek approval for the combination therapy....

Spooked by yield rise, ECB wary of changing message again

European Central Bank policymakers are wary of making any new change to their policy message in April after small tweaks this month upset investors and raised the specter of a surge in borrowing costs for the bloc’s indebted periphery. One ECB source said the...